Comprehensive Analysis of Anticoagulant Therapy in Patients with Isolated Atrial Flutter.

Limited comparative data exist regarding the risk of cardiogenic emboli in patients with isolated atrial flutter (AFL). Some studies suggest a lower complication risk in AFL compared to atrial fibrillation (AFib), but methodological limitations and conflicting reports necessitate a comprehensive investigation. Our analysis proposes that isolated AFL carries a lower risk of ischemic events and left atrial thrombus formation than AFib.

G-Quadruplex Forming DNA Sequence Context Is Enriched around Points of Somatic Mutations in a Subset of Multiple Myeloma Patients.

Multiple myeloma (MM) is the second most common hematological malignancy, which remains incurable despite recent advances in treatment strategies. Like other forms of cancer, MM is characterized by genomic instability, caused by defects in DNA repair. Along with mutations in DNA repair genes and genotoxic drugs used to treat MM, non-canonical secondary DNA structures (four-stranded G-quadruplex structures) can affect accumulation of somatic mutations and chromosomal abnormalities in the tumor cells of MM patients.

Particleboard Creation from Agricultural Waste Residue of Seed Hemp.

In this research, agricultural residue of seed hemp variety "Adzelvieši" was used to create hemp particleboard samples. Hemp was grown in three experimental fields where it was observed that after seed harvesting, 3.5 tonnes of hemp stems per hectare remained.

Boosted excitation of the fifth cyclotron harmonic based on frequency multiplication in conventional gyrotrons.

We discovered a specific property of the eigenmodes of a cylindrical waveguide, due to which efficient mode excitation at ultrahigh (s=4n+1, n is integer) multiples of the gyrofrequency can be provided by a polyhelical weakly relativistic electron beam, standardly used for gyrotron operation. In the proof-of-principle experiment with a V-band gyrotron driven by a 25-keV, 2-A beam, about 100 mW radiation power at the fifth cyclotron harmonic (0.22 THz) has been detected in the cw regime.

Modulation instability of an electromagnetic wave interacting with a counterpropagating electron beam under condition of cyclotron resonance absorption.

In this paper, transmission of a monochromatic wave through a counterpropagating electron beam under the condition of cyclotron resonance absorption is studied by theoretical analysis and numerical simulation. Conditions of the modulation instability (MI) are analyzed. The MI strongly affects the regimes of transmission.