The neuroplasticity potential is reduced with aging and impairs during neurodegenerative diseases and brain and visual system injuries. This limits the brain's capacity to repair the structure and dynamics of its activity after lesions. Maximization of neuroplasticity is necessary to provide the maximal CNS response to therapeutic intervention and adaptive reorganization of neuronal networks in patients with degenerative pathology and traumatic injury to restore the functional activity of the brain and retina.
View Article and Find Full Text PDFUnder virtual labor migration, or telemigration, in the expert community it is customary to understand remote work or the provision of services that are carried out in a cross-border format. The presence of the word in this term logically prompts us to consider the designated process in a migration context. From the standpoint of the concept of migration transition, the spread of virtual migration can be interpreted as a new link in the chain of mobility transformations generated by multifaceted digital transformations.
View Article and Find Full Text PDFForced mobility and forced immobility are not just polar types of involuntary migration behavior. According to the author, they are closely interconnected and are like communicating vessels, being a product of common causes: conflict, violence, and unfavorable environmental processes, the action of which can be both stimulating and hindering movement. The decision to leave or stay is influenced by a wide range of objective factors and subjective circumstances, including values, preferences, emotions, irrationality, etc.
View Article and Find Full Text PDFUnlabelled: Various animal models of atrophy of retinal pigment epithelium (RPE) are created in order to study certain aspects of geographical atrophy in humans. To study the effects of new methods of therapy, it is necessary to determine the objective functional markers of structural changes in the retina.
Purpose: To determine the alterations in activity of the retina that characterize its remodeling in induction of RPE atrophy.
Unlabelled: The clinical sugnificance of electroretinogram interpretation depends heavily on the employed mathematical apparatus. Currently, conventional calculation of the amplitude and time parameters of electroretinogram (ERG) components and their relations (indices), as well as analysis of the frequency spectrum of the signal are becoming insufficient for interpretation of the obtained data. New approaches to diagnostics are currently being developed, using, among other things, expert systems, and neural network and simulation models.
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