[Dopaminergic regulation of the hypothalamo-hypophyseal system in patients with hypophyseal adenomas].

A study was made of the state of the hypothalamohypophyseal system in patients with different types of chromophobe adenoma. Altogether 62 patients were examined using metoclopramide and Parlodel tests (38 patients were with somatotropinoma, 13--with prolactinoma, 11--with somatotropinoma with hyperprolactinemia). The time course of STH, PRL and TSH secretion in the blood was investigated.

[Long-term use of parlodel in acromegaly].

The authors studied the basal and L-DOPA-stimulated levels of STH and basal level of prolactin in blood serum of 128 patients presenting with acromegaly. The basal levels of STH and prolactin were found to be elevated in the majority of patients with an active disease stage. Long-term (for 5-6 years) therapy with parlodel (2.