Publications by authors named "I V Osis"

A cytophotometric technique to quantitate the content of apolipoprotein B (apo B) in cryostate sections of human aorta is described. The method is based on the comparison of different regions of the sections stained by indirect immunoperoxidase technique, using antibody to apo B. It has been found that the optical density of stained intimal layer was 8-22 times higher than that of the stained aortic media, which in its turn, differed from the control values.

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Endothelium-derived relaxing factor (EDRF) exerted no inhibitory effect on papillary muscles or the rat portal vein. Externally applied acetylcholine did not reach aorta endothelium to stimulate the EDRF release in rabbits, nor bradykinin in the pig coronary artery segments. Acetylcholine penetrated, however, canine femoral artery wall and stimulated the release of EDRF.

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A study was made of 606 specimens from dead males aged 20 to 39. The frequency and area of rhythmical structures (RS) of lipid spots and fibrous patches of aorta were determined after staining of aortae with Sudan IV. RSs were revealed in persons aged 20-29 and 30-39 in 70%.

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