Publications by authors named "I V Nikolaeva"

Article Synopsis
  • - Opsoclonus is an involuntary eye movement disorder characterized by rapid, chaotic, and multidirectional eye movements, often linked to myoclonus and commonly caused by a paraneoplastic process or viral infections.
  • - A case study highlights a 26-year-old man with symptoms resembling encephalitis, including balance issues, tremors, and jerking eye movements, leading to the diagnosis of opsoclonus-myoclonus syndrome after testing positive for West Nile virus.
  • - Despite initial treatment with acyclovir and dexamethasone, the patient experienced severe symptoms for two weeks but gradually improved with rehabilitation, emphasizing the importance of recognizing West Nile virus as a potential cause of this syndrome.
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Aim: The search for etiopathogenetic agents to prevent the development of severe and extremely severe COVID-19 remains relevant. A placebo-controlled randomized clinical trial was conducted to evaluate the efficacy and safety of the antibody-based biological drug (Raphamin).

Materials And Methods: 785 outpatients 18-75 y.

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At the selected frequencies from 0.3 to 10 THz we measured the two-dimensional (2D) distributions of fluence and polarization of terahertz (THz) emission from a single-color femtosecond filament. At the majority of frequencies studied, the THz beam has a donut-like shape with azimuthal modulations and radial polarization.

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It is known that the saturation ratio of transferrin (Tf) with iron in human blood is an important clinical parameter. Specific antibodies can be used to analyze subtle changes in the relative abundance of different forms of transferrin potentially associated with a pathological process. Recently, the authors of this study were able to obtain and characterize highly specific single-domain antibodies (nanobodies) that predominantly recognize the iron-saturated (holo-Tf) or iron-unsaturated (apo-Tf) form of transferrin.

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Objective: The aim: To study the family influence on the formation of children's motivation for a healthy lifestyle.

Patients And Methods: Materials and methods: The medical and sociological study among parents was conducted to assess their children's adherence to the principles of a healthy lifestyle and the influence of the family on the formation of children's motivation for a healthy lifestyle. The survey was conducted using a specially designed questionnaire using Google Forms.

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Synopsis of recent research by authors named "I V Nikolaeva"

  • - I V Nikolaeva's recent research spans a variety of medical and scientific fields, including neurology, infectious diseases, cancer diagnostics, and health psychology, showcasing a multidisciplinary approach to addressing complex health issues.
  • - Highlights of the findings include the identification of opsoclonus-myoclonus syndrome in relation to West Nile virus, as well as a study demonstrating the efficacy of an antibody-based therapy (Raphamin) for mitigating severe COVID-19 outcomes.
  • - Noteworthy contributions also include the exploration of novel diagnostic techniques for bladder cancer through transferrin analysis using nanobodies, and an investigation into the familial influences on children's motivations for maintaining a healthy lifestyle.