Neutrophil extracellular traps characterize caseating granulomas.

Tuberculosis (TB) remains one of the top 10 causes of death worldwide and still poses a serious challenge to public health. Recent attention to neutrophils has uncovered unexplored areas demanding further investigation. Therefore, the aim of this study was to determine neutrophil activation and circulatory neutrophil extracellular trap (NET) formation in various types of TB.

[FEATURES OF THE COMPLICATED COURSE OF NON-HOSPITAL VIRAL COVID-19 PNEUMONIA].

The purpose of this work was to demonstrate clinical observations of the features of the complicated course of community-based viral COVID-19 pneumonia. Patients were referred for treatment with a complicated course of pneumonia from other medical institutions, where they were treated 2-3 months ago. The most serious complications are given - the formation of bullosa pulmonary emphysema ("disappearing lung syndrome"), which can occur at different periods of the disease.

[INFORMATIVITY OF COMPUTER DENSITOMETRY FOR ASSESSING THE DEGREE OF ACTIVITY OF THE INFLAMMATORY PROCESS IN PULMONARY TUBERCULOMAS].

In order to establish the levels of densitometric indicators of CT of the chest for various degrees of activity of a specific inflammatory process, the histopathological findings of the resected material were analyzed in 65 patients aged 24 to 60 years, 39 of them men, 25 women operated on pulmonary tuberculosis with a measurement of their densitometric indicators on CT of the chest. It is proved that computer densitometry is an objective non-invasive research method that allows you to establish with high confidence the degree of activity of a specific inflammatory process. The study of the average, minimum and maximum values of the density indicator on a fixed area of the axial section of the CT scan actually reflects the histological structure of the focus and allows you to identify areas with high activity of a specific inflammatory process.

[Morphological peculiarities of exudative pleuritis of unknown origin according to the data of closed pleural puncture biopsy].

The results of cytological and histological investigations of pleural biopsy, obtained using the closed transthoracic puncture pleural biopsy (CTPPB) method in patients, suffering the syndrome of exudative pleuritis of unknown origin, were presented. There were analyzed 69 observations. Peculiarities of histological assessment of pleural biopsies were noted, characteristic morphological signs, observed in the main pleural pathological processes: nonspeciphic inflammation, tuberculous inflammation, tumoral and metastatic affection.

[Modern tendencies of malignant pleural effusions epidemiology].

The during 7 years 258 patients with malignant effusion (ME) of different ethiology were treated in clinic, that composed 13.8% among all patients with pleural effusion. It was discovered the increase of this complication frequence in 1.