[Results of deconstructive endovascular surgery in treatment of large and giant intracranial aneurysms].

Aim: To clarify the indications for deconstructive endovascular surgery in patients with large and giant intracranial aneurysms and to evaluate short-term and long-term postoperative outcomes.

Material And Methods: The study was based on a retrospective analysis of the treatment results in 50 patients with large (15-25 mm) and giant (more than 25 mm) intracranial aneurysms, aged from 18 to 75 years, who were treated at the Burdenko Neurosurgical Institute in 2002-2014. The patients underwent a balloon occlusion test (BOT) in various modifications before stationary occlusion of the carrier artery.

[Beta-endorphin in pituitary adenomas before surgery and in the postoperative period].

The content of beta-endorphin, ACTH, and cortisol was studied in 20 patients with hormonally-active, somatotropic hormone-secreting, prolactin-secreting, and hormonally inactive adenomas of the hypophysis before operation and in the early postoperative period. Before operation the basal level of hormones was within normal physiological fluctuations. In a favourable postoperative period the beta-endorphin level increased, while the ACTH content was low.