[Prophylaxis and correction of inflammatory complications in peritonitis, depending on severity of enteral insufficiency].

There were examined 54 patients, in whom peritonitis of various etiology was diagnosed. Clinical, biochemical, immunological and other investigations were conducted for estimation of the enteral insufficiency syndrome severity. Basing on the analysis of the data obtained and criterions of the patient common state there was determined the occurrence risk for inflammatory complications (IC).

[Effects of amyloid-β peptide Aβ(25-35) on glycolytic and antioxidant enzymes of different ages].

Amyloid-β peptide Aβ(25-35) was shown to cause lysis of rat erythrocytes of different ages. The toxicity of Aβ(25-35) positively correlated with both the erythrocyte age andthe peptide concentration. The activity of glycolytic, antioxidant, and Na+/K(+)-ATPase enzymes decreased with erythrocyte aging in vivo.

[Differences between cerebellum and hippocampus in antioxidant system].

The effect of portacaval shunting on the antioxidant status of the cerebellum and hippocampus was studied in rats using standard methods of enzymatic analysis. Endogenous ammonia levels and activities of eight antioxidant enzymes were shown to be unequal in two brain regions and to respond differently upon portal-systemic shunt surgery.

[Arginase, nitrates, and nitrites in the blood plasma and erythrocytes in hypertension and after therapy with lisinopril and simvastatin].

Arginase activity in erythrocytes is higher in patients with arterial hypertension and atherosclerosis as compared with healthy people. Therapy with either lisinopril alone or in combination with simvastatin for 3-6 months causes a decrease in the arginase activity to the control level. Both the monotherapy and the combination therapy increased the concentrations of NO2(-), NO3(-), and total NOO2(-) + NO3(-)in the plasma of hypertensive patients.