Publications by authors named "I V Kameshwar Rao"
Chloride is the most abundant extracellular anion; however, abnormalities of serum chloride (dyschloremia) are often overlooked. This study aimed to study the association of dyschloremia with AKI and major adverse kidney events at Day 30 (MAKE30) in critically ill patients with sepsis. This prospective single-center cohort study included adult patients with sepsis admitted in a tertiary care hospital in India.
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- Haematological abnormalities, particularly post-transplant anemia (PTA), are common among renal transplant recipients, with a peak prevalence of 98% in the first week post-surgery.
- Other issues included leukopenia, thrombocytopenia, and pancytopenia, often caused by medications and infections.
- Despite the high incidence of PTA initially, graft function was stable and similar among patients with and without anemia at six and 12 months post-transplant.
Objectives: The existing biomarkers used to promptly identify graft dysfunction after kidney transplantation lack consistency. Neutrophil gelatinase-associated lipocalin (NGAL) appears to be a promising biomarker but its levels measured from serum and urine have demonstrated varying predictive values. Our study aimed to explore the potential of NGAL as a biomarker in predicting graft dysfunction in kidney transplant patients, including live and deceased donor recipients.
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- A significant portion of heart failure patients (around 30%) do not respond to cardiac resynchronization therapy (CRT), especially those with QRS durations between 120-149 ms who receive inconsistent benefits.
- A study evaluated the effectiveness of cardiac contractility modulation (CCM) in improving heart failure-related hospitalizations, left ventricular ejection fraction (LVEF), and quality of life in patients with this specific QRS duration.
- Results showed that CCM reduced hospitalizations by 72%, improved LVEF by 7%, and positively affected quality of life, with outcomes similar to those seen in patients with shorter QRS durations; mortality within the first year was not significantly different from predictions.