Publications by authors named "I V Il'ina"

We present a method for the generation of terahertz (THz) pulses with a high optical-to-THz conversion efficiency and a smooth spectrum. The method is based on the optical rectification of near-infrared femtosecond laser pulses with a wavelength of 1240 nm in a mosaic combined crystal, consisting of two pieces of nonlinear organic crystals, OH1 and DSTMS. The mosaic combined crystal produces a relatively smooth spectrum in the 0.

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Despite of great number of investigations in the area of tinea pedis, question is opened: to what extent dermatophyte fungi are spread among modern population and does their occurrence interrelated with host age? Investigated group included 99 volunteers from 14 to 73 years old. Skin scales were collected from heel area of foot, and signs of heel skin trouble were expressed in points. In contrast to usual laboratory microscope magnification x900 we worked at x1750, what allowed to estimate not only fungal, but bacterial forms too.

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Article Synopsis
  • Researchers discovered two new types of TDP1 inhibitors that can effectively inhibit the TDP1 enzyme, crucial for DNA repair, at low concentrations, with the strongest compound showing an IC value of 0.65 μM.
  • The inhibitors were synthesized from monoterpene compounds and they demonstrated a synergistic effect when tested with the cancer drug topotecan in HEK293FT cells with functional TDP1.
  • This synergy suggests that using non-toxic inhibitors alongside existing cancer therapies can improve treatment effectiveness while minimizing harmful side effects.
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The methods for quantification of highly potent analgesic agent (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol in rat whole blood and plasma were developed and validated using dried matrix spots (DMS) or fabric phase sorptive extraction (FPSE) techniques in combination with LC-MS/MS. 2-Adamantylamine hydrochloride was used as an internal standard (IS). Chromatographic separation was carried out on a reversed-phase column (2.

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