Publications by authors named "I V Fefelova"

State Educational Institution for Professional Education - Prof. Voyno-Yasenetzkiy's High School of Krasnoyarsk State Medical Academy of Russian Public Health Ministry. We carried out the analysis of the changes in the spectrum of neutral lipoids and phospholipoids in blood serum as a response to meals in girls of different somatotypes.

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195 girls aged 14-16 years with the disturbances of sexual development of chromosomal and non-chromosomal genesis were examined. In girls with Shereshevsky-Turner syndrome, the body mass and length, as well as the relative adipose tissue content, were significantly decreased as compared with those in girls with the disturbances of sexual development of non-chromosomal genesis. The differences in somatotype distribution between these groups were detected.

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We carried out a comparative analysis of activity of enzymes characterizing metabolic (SDG) and catabolic (KF) processes in immune system cells of 195 girls with sexual maturation disturbance of chromosome (Shereshevsky-Terner syndrome--STS) and non-chromosome genesis. KF activity was similar in the compared groups and 14 control girls, while SDG activity and FSH levels were much higher in STS girls compared to control girls and girls with amenorrhea of non-chromosome genesis. Thus, FSH has a considerable influence upon metabolic parameters of immune system cells.

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Anthropometric parameters, body composition and somatotype distribution were examined in 91 girl with Shereshevsky-Turner syndrome, which develops as a result of sex chomosome anomaly. Somatotype definition was carried out using V.P.

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A new simple and prompt procedure for measuring acrylamide (propenamide, PA) in PA-derived mercapturic acid, such as N-acetyl-S-(2-propenamide)-L-cysteine (N-Ac-PAC), and in hemoglobin (Hb) and plasma protein adducts in the rats expose to PA was developed, by employing gas chromatography (GC). PA in mercapturic acids or proteins was liberated on high-temperature heating in an injector port during the working procedure of a GC capillary after preoxidation of sulfur atoms in PA-bound cysteine to a sulfoxide form with hydrogen peroxide and analyzed. This method resulted in 87% of PA in authentic N-Ac-PAC.

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