The immunologic phenotype of blast cells was studied in 66 patients with chronic myeloleukemia (CML) in the stage of blast crisis. cALL antigen was determined with the aid of rabbit antiserum, Ia-like antigen with the aid of monoclonal antibodies IKO-I; part of the patients showed cytoplasmic immunoglobulins. As regards the expression of the immunologic markers, the patients were divided in 2 subgroups: the lymphoid one having cALL antigen and/or the cytoplasmic chain of immunoglobulins, and the nonlymphoid having no such markers.
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