Charge Transfer Chromophores Derived from 3d-Row Transition Metal Complexes.

A series of new charge transfer (CT) chromophores of "α-diimine-M-catecholate" type (where M is 3d-row transition metals-Cu, Ni, Co) were derived from 4,4'-di--butyl-2,2'-bipyridyl and 3,6-di--butyl--benzoquinone () in accordance with three modified synthetic approaches, which provide high yields of products. A square-planar molecular structure is inherent for monomeric () and () chromophores, while dimeric complex () units two substantially distorted heteroleptic D-M-A (where D, M, A are donor, metal and acceptor, respectively) parts through a donation of oxygen atoms from catecholate dianions. Chromophores - undergo an effective photoinduced intramolecular charge transfer (λ = 500-715 nm, extinction coefficient up to 10 M·cm) with a concomitant generation of a less polar excited species, the energy of which is a finely sensitive towards solvent polarity, ensuring a pronounced negative solvatochromic effect.

Complexes of Metal Halides with Unreduced -(Imino)quinones.

A series of complexes of metal halides with unreduced quinone-type ligands have been synthesized and characterized in detail. The 3,6-di--butyl--benzoquinone () and 4,6-di--butyl--aryl-substituted -iminobenzoquinones (-) (aryl is 2,6-dimethylphenyl in , 2-methyl-6-ethylphenyl in , 2,6-diethylphenyl in , and 2,6-diisopropylphenyl in ) were used to obtain the molecular complexes with metal 12 group halides as well as with indium(III) iodide. The molecular structures of five complexes, bearing an unreduced form of redox-active ligand, have been established by single-crystal X-ray analysis.

Heteroleptic La Anilate/Dicarboxylate Based Neutral 3D-Coordination Polymers.

Three new 3D metal-organic frameworks of lanthanum based on mixed anionic ligands, [(La(pQ)(BDC))·4DMF], [(La(pQ)(DHBDC))·4DMF], [(La(CA)(BDC))·4DMF] (pQ-dianion of 2,5-dihydroxy-3,6-di-tert-butyl-para-quinone, CA-dianion of chloranilic acid, BDC-1,4-benzenedicarboxylate, DHBDC-2,5-dihydroxy-1,4-benzenedicarboxylate and DMF-N,N'-dimethylformamide), were synthesized using solvothermal methodology. Coordination polymers demonstrate the rare or topology of a 3D framework. The homoleptic 2D-coordination polymer [(La(pQ))·4DMF] was obtained as a by-product in the course of synthetic procedure optimization.

[Possibilities of improving the effectiveness of therapy in patients with chronic cerebral ischemia against the background of COVID-19].

Objective: To study the possibility of improving the efficacy of treatment with mexidol in COVID-19 patients with chronic cerebral ischemia (CCI).

Material And Methods: Three hundred and four patients with CCI and COVID-19 were observed, group 1 (=152) consisted of patients receiving basic therapy and mexidol, group 2 (=152) received only basic therapy. Mexidol was administered intravenously for 14 days, 500 mg (10 ml) per 400 ml of saline solution, then Mexidol FORTE 250 was administered in a dose of 250 mg 3 times a day for 2 months.

Tetrahedral nickel(ii) and cobalt(ii) bis-o-iminobenzosemiquinonates.

The new bis-o-iminobenzosemiquinonate nickel and cobalt complexes (imSQt-Bu)2M (M = Ni (1), Co (2)), where imSQ is a radical anion of 4,6-di-tert-butyl-N-(tert-butyl)-o-iminobenzoquinone, were synthesized and characterized in detail. The molecular structures of 1 and 2 have been established by single-crystal X-ray analysis. The metal atoms in 1 and 2 have a distorted tetrahedral environment, and the dihedral angles between the planes of two radical imSQ ligands are approximately 80° in both complexes.