[The relationship between certain phenotypic traits and the function of individual links of immunity in children with acute pneumonia].

While studying immunogenetic indexes in 250 children with acute pneumonia, it is revealed that there is a connection between their phenotypic peculiarities (blood group B/III/, MN, P--dry type of ear-wax, low indexes of mass of the body and high ones of the body length during birth) and indexes of T-lymphocytes and immunoglobulins of blood serum A, M, G. It has permitted recommending to perform purposeful therapeutic and prophylactic measures including immunocorrection for these children.

[A case of Holt-Oram syndrome].

Description of a rare hereditary heart disease in a newborn (heart-hand symptom complex: changes of the shape and structure of a forearm with the absence of thumb and finger V plus atrial septal defect) is presented. The combined effect of genetic and environmental influences is regarded as a cause of the syndrome.

[Changes in protease inhibitor balance of the bronchoalveolar secretion in children with inflammatory lung diseases].

As many as 95 children staying at a clinic were examined for the proteinase-inhibitory balance of the bronchoalveolar secretion in acute pneumonia, relapsing bronchitis and chronic pneumonia in the stage of exacerbation. In all the three diseases, there was a rise of the protein content, trypsin-like activity and alpha 2-macroglobulin level. In acute pneumonia, free antitryptic activity and the level of acid-resistant inhibitors increased; in relapsing bronchitis, these parameters remained within the limit of control values, and in chronic pneumonia, they significantly reduced.