Publications by authors named "I Ugurlu"
Purpose: In advanced breast cancer, endocrine therapy is preferred in the absence of visceral crisis. Cyclin-dependent kinase inhibitors (CDKi) are the gold standards. The selection of subsequent treatments after CDKi treatment is still controversial, and the efficacy of everolimus (EVE) combinations is unknown.
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- Triple negative breast cancer (TNBC) often recurs after treatment, particularly in those with residual disease post-chemotherapy, and capecitabine is commonly used as a follow-up treatment for these patients.! -
- A study analyzed 170 TNBC patients who received capecitabine after neoadjuvant chemotherapy, finding a 30% recurrence rate and 18% death rate, with a 3-year disease-free survival (DFS) of 66% and overall survival (OS) of 74% in the cohort.! -
- Results indicated that while capecitabine's effectiveness was lower than past studies, certain patients, especially those with specific residual disease characteristics, could still benefit from it,
Comparison of immunogenicity for Sinovac-CoronaVac vaccine vs. natural infection during cancer treatment.
Eur Rev Med Pharmacol Sci
May 2023
Objective: Efficacy of the COVID-19 vaccines in cancer patients, especially during their active treatment, are lacking. Most of the studies in the literature compared the immunity in cancer patients with a cross-sectional cohort or retrospectively. Our study investigated Sinovac-CoronaVac COVID-19 vaccine immunogenicity and compared it with natural COVID-19 disease in cancer patients during their cancer therapy.
View Article and Find Full Text PDFBackground: Lateral elbow tendinopathy (LET) is one of the most common lesions of the upper extremity. The level of evidence from studies on LET treatment protocols is insufficient.
Objective: The aim of this study was to compare the acute effects of mobilization with movement (MWM) and muscle energy technique (MET) on pain, grip strength, and functionality in patients diagnosed with LET.
Although adipose tissue largely plays a role in the etiopathogenesis of metabolic syndrome (MS), which is an inflammatory process, the skeleton may also contribute to this process through osteocalcin (OC), which is a bone-derived protein. In this study, we aimed to evaluate OC levels in postmenopausal women with MS and to investigate the association of OC levels with the metabolic and inflammatory parameters. Thirty-five postmenopausal women diagnosed with MS were recruited for the study.
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