Publications by authors named "I Tsukamoto"
Article Synopsis
- A microdialysis study was conducted on mice to investigate how local perfusion of COA-Cl affects dopamine (DA) and its metabolites in the dorsal striatum.
- Perfusion with COA-Cl at concentrations of 0.1 and 0.5 mM significantly increased extracellular levels of DA, 3-methoxytyramine (3-MT), and homovanillic acid (HVA), indicating a dose-dependent effect, while 0.05 mM had no significant impact.
- The addition of the MAO inhibitor clorgyline revealed that COA-Cl enhances DA metabolism, suggesting it influences dopamine levels through increased DA release and/or activation of MAO in the brain.
Article Synopsis
- Acute Compartment Syndrome (ACS) is a serious condition caused by high pressure within muscle compartments, traditionally diagnosed using a needle method, which can be difficult and slow, prompting exploration of Shear Wave Ultrasound Elastography (SWE) as a faster, less invasive alternative.
- A study with 32 turkeys tested the correlation between SWE readings and intra-muscle-compartment pressure by gradually increasing pressure in the muscly while measuring SWE values, muscle function, and gait over time.
- Results showed a strong correlation (R2 = 0.91) between SWE values and actual pressure, with significant changes in muscle function and histological damage observed in groups subjected to higher pressure for extended periods.
Background/aim: The present study investigated the anticancer effects of intraperitoneally administered D-allose in in vivo models of head and neck cancer cell lines.
Materials And Methods: To assess the direct effects of D-allose, its dynamics in blood and tumor tissues were examined.
Results: D-allose was detected in blood and tumor tissues 10 min after its intraperitoneal administration and then gradually decreased.
Objective: The purpose of this study was to investigate the consistency of the changes in the elastic modulus measured with ultrasound shear wave elastography (SWE) with changes measured through mechanical testing using tendons that were artificially altered by chemical modifications.
Methods: Thirty-six canine flexor digitorum profundus tendons were used for this experiment. To mimic tendon mechanical property changes induced by tendinopathy conditions, tendons were treated with collagenase to soften the tissue by collagen digestion or with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC) to stiffen the tissues through chemical crosslinking.
is a parasitic protozoan with roles in pathogenicity of intestinal amoebiasis. trophozoites lack functional mitochondria and their energy production depends mostly on glycolysis. D-Glucose has a pivotal role in this process and trophozoites store this sugar as glycogen in glycogen granules.
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