Publications by authors named "I Tron"
Long-term outcomes and predictors of disabling disease in a population-based cohort of patients with incident Crohn's disease diagnosed between 1994 and 1997.
Clin Res Hepatol Gastroenterol
November 2022
Background: The identification of early prognostic factors during Crohn's disease (CD) remains needed for physician decision-making to minimize structural bowel damage, which this study aimed to assess in a population-based setting.
Methods: All incident cases of CD were prospectively registered from 1994 to 1997 in Brittany, a limited area of France. All charts of patients were reviewed from the diagnosis to the last clinic visit in 2015.
Article Synopsis
- The study aimed to explore the incidence, outcomes, and predictors of perianal Crohn's disease (PCD) in a specific population in Brittany, France, by tracking patients from 1994 to 2015.
- Out of 272 patients with Crohn's disease, 18.7% had PCD at diagnosis, and over time, 34% developed PCD, with risks of conditions like anal ulceration and fistulizing PCD increasing over the years.
- The findings suggest that PCD is common in Crohn's disease and highlight the importance of targeted treatment strategies for early symptoms to prevent more severe complications like fistulizing disease.
Background: In France, although children aged less than 15 years with cancer are usually referred to pediatric oncology centers, adolescents may be treated at pediatric or adult oncology centers. The objective was to compare survival according to their site of treatment.
Procedure: Using population-based registration, 15- to 19-year-old patients diagnosed with cancer in 2006 or 2007 and living in six French regions (accounting for 41% of the French population) were included.
Background And Purpose: Multiple sclerosis (MS) prognosis remains a challenge for both patients and physicians. Complementary to natural history studies, updated population-based data from the first event suggestive of MS, at the time of the first approved disease modifying drug (DMD), are needed. Our objective was to provide a 10-year history of MS from clinical onset at time of first approved DMDs in a population-based cohort.
View Article and Find Full Text PDFObjectives: To report on multiple sclerosis (MS) incidence in Brittany, north-western France.
Materials & Methods: From 2000, we set up a population-based register for patients presenting a putative incident MS (PIMS), that is first symptoms compatible with MS onset. We used 3 medical sources of case ascertainment (neurologists, CSF, regional MS-Clinic).