Publications by authors named "I Temel Yuksel"
Background: To compare the long-term safety and efficacy of Adalimumab (ADA) and Infliximab (IFX) agents in biologic-naive patients with Ulcerative colitis (UC).
Methods: The key focus was on specific outcomes such as the requirement of hospitalization due to UC, colectomy, steroid administration, and severe infections that led to the discontinuation of therapy.
Results: Anti-TNF treatment was initiated in 208 of the 475 patients with ulcerative colitis.
Article Synopsis
- The study examines the best timing for endoscopy in elderly patients (65+) experiencing nonvariceal upper gastrointestinal bleeding (NVUGIB) and its effect on clinical outcomes.
- Very early endoscopy (within 12 hours) showed significantly lower 30-day mortality rates and reduced need for surgical interventions compared to late endoscopy (after 24 hours).
- Patients who had late endoscopy were more likely to experience rebleeding, indicating timing is crucial for improving patient outcomes in this demographic.
Article Synopsis
- The study analyzed risks and clinical outcomes of endoscopic retrograde cholangiopancreatography (ERCP) in elderly (≥75 years) versus younger patients, finding 22.8% of participants were elderly.
- It revealed significant comorbidities and a higher prevalence of periampullary diverticulum (PAD) in the elderly, though key procedural metrics like cannulation technique and success rates were similar across age groups.
- Despite comparable complication rates, elderly patients experienced longer hospital stays and worse outcomes after complications, highlighting prolonged cannulation time as a notable risk factor.