Focus on using nanopore technology for societal health, environmental, and energy challenges.

With an increasing global population that is rapidly ageing, our society faces challenges that impact health, environment, and energy demand. With this ageing comes an accumulation of cellular changes that lead to the development of diseases and susceptibility to infections. This impacts not only the health system, but also the global economy.

Unique skin manifestations of COVID-19: Is drug eruption specific to COVID-19?

• COVID-19 is associated with specific skin manifestations and drug eruption. • This case shows COVID-19–related drug eruption and specific clinical features. • Drug eruption preceding COVID-19 symptoms may facilitate early diagnosis.

Imidate as the Intact Directing Group for the Cobalt-Catalyzed C-H Allylation.

Cobalt-catalyzed C-H allylation reactions of NH-free benzimidates using vinylcyclopropanes or allyl carbonate are reported. The reactive and relatively unstable imidate groups remain intact during the C-H allylations to afford functionalized imidates without dealcoholizations. The thus obtained allylated imidate was subsequently converted into other heterocyclic structures through a following C-H functionalization reaction, demonstrating the synthetic utility of this method.

Draft Genome Sequence of Porphyromonas gingivalis Strain 381 Okayama (381OKJP) Stock Culture.

We report the draft genome sequence of Porphyromonas gingivalis strain 381 Okayama (381OKJP). The strain, obtained from the Socransky collection, has been used for experimentation since 1987. This sequence allows for comparisons to other sequenced 381 strains to observe acquisition of mutations and genome rearrangements in a commonly used laboratory strain.