Publications by authors named "I TAKI"

Aim: Developmental disabilities (DD) often persist into adulthood, necessitating early and continuous treatment. Although pharmacotherapy is a viable treatment option, managing medication can be challenging. Prior research has not explored medication use among patients with DD in Japan.

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Article Synopsis
  • The use of food thickeners with ciprofloxacin can alter the drug’s appearance and slow down its dissolution, potentially affecting its effectiveness and posing economic concerns in healthcare.
  • A study was conducted on healthy Japanese males to compare how different methods of taking ciprofloxacin (with water, thickened water, and crushed tablets in thickened water) affect drug absorption.
  • Results showed that while thickened water changed drug absorption, crushed tablets in thickened water provided similar absorption metrics as tablets with regular water, though crushing may risk losing active ingredients and requires careful consideration.
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Background & Aims: Celiac disease (CD) mass screening remains controversial in part because of a paucity of data to support its benefit. The Autoimmunity Screening for Kids study is a mass screening study for pediatric CD and type 1 diabetes in Colorado.

Methods: This study prospectively follows up children ages 1 to 17 years who screened positive for tissue transglutaminase IgA autoantibodies in the Autoimmunity Screening for Kids study subsequently referred for diagnostic evaluation.

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Attention deficit/hyperactivity disorder (ADHD) is a common developmental disorder. This study aims to clarify the timing of diagnosis of ADHD in working-age workers with psychiatric comorbidities using large claims data in Japan. Based on a literature survey, we identified 10 typical comorbidities of ADHD.

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Background And Purpose: Type 1 diabetes affects over 200,000 children in the United States and is associated with an increased risk of cognitive dysfunction. Prior single-site, single-voxel MRS case reports and studies have identified associations between reduced NAA/Cr, a marker of neuroaxonal loss, and type 1 diabetes. However, NAA/Cr differences among children with various disease complications or across different brain tissues remain unclear.

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