Publications by authors named "I T Tofolean"
Recent advances have highlighted the gut microbiota as a significant contributor to the development and progression of atherosclerosis, which is an inflammatory cardiovascular disease (CVD) characterized by plaque buildup within arterial walls. The gut microbiota, consisting of a diverse collection of microorganisms, impacts the host's metabolism, immune responses, and lipid processing, all of which contribute to atherosclerosis. This review explores the complex mechanisms through which gut dysbiosis promotes atherogenesis.
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- Intestinal endometriosis is a rare but significant cause of intestinal obstruction, and this case report emphasizes the challenges in diagnosis and management associated with the condition.
- A 50-year-old woman experiencing severe abdominal pain and symptoms of blockage underwent diagnostic imaging, which revealed small bowel dilation and an ileal volvulus, ultimately leading to surgical intervention.
- Post-surgery, the patient's recovery was gradual, with a later successful reversal of an ileostomy, highlighting the need for awareness of intestinal endometriosis in women with gastrointestinal symptoms and the importance of prompt surgical management.
Background: Pseudoexfoliation syndrome (PEX) is a common age-related ocular condition characterized by the accumulation of a fibrillar, pseudoexfoliative material on the anterior segment of the eye. This study aims to investigate the histopathological characteristics of pseudoexfoliative material within different ocular structures, including the eyelid, conjunctiva, and anterior lens capsule.
Methods: A total of 32 anterior lens capsules, 3 eyelid fragments, and 12 conjunctival specimens were obtained from patients clinically diagnosed with PEX during ocular surgeries at the Onioptic Hospital of Ophthalmology.
Article Synopsis
- The study examined the results of sequential pars plana vitrectomy for treating retinal detachment with macular holes in non-highly myopic patients from 2017 to 2023.
- Out of 980 patients, 10 underwent this two-step surgical process, which included repairing the retinal detachment followed by macular hole closure using a specific technique, leading to high rates of success.
- The findings showed a 90% initial retinal reattachment rate, 100% after the second surgery, complete macular hole closure in all cases, and a significant improvement in visual acuity after treatment.
Background: Spaceflight-Associated Neuro-Ocular Syndrome (SANS) is a complex pathology threatening the health of astronauts, with incompletely understood causes and no current specific functional diagnostic or screening test. We investigated the use of the differential performance of the visual system (central vs. perimacular visual function) as a candidate marker of SANS-related pathology in a ground-based microgravity analogue.
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