Publications by authors named "I T Sharpe"

Objective: Electroconvulsive therapy (ECT) is an evidence-based treatment for schizophrenia when anti-psychotic medications do not sufficiently control symptoms of psychosis or rapid response is required. Little is known about how it is used in routine clinical practice. The aim of this study was to identify the association of demographic and clinical characteristics with administration of ECT for schizophrenia spectrum disorders (SSD).

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Article Synopsis
  • A retrospective cohort study in Ontario compared the rates of neurological events, such as hospitalization or emergency room visits, after COVID-19 vaccination among different ethnic groups from December 2020 to June 2021.
  • The study found that crude rates of neurological issues like Bell's palsy, ischemic stroke, and intracerebral hemorrhage were lower in both Chinese and South Asian populations compared to Other ethnic groups after the first vaccine dose.
  • After adjusting for factors like age, sex, and vaccine type, the rates were similar across groups, suggesting that vaccination should be encouraged for everyone, regardless of ethnicity.
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Individuals with disabilities may require specific medications in pregnancy. The prevalence and patterns of medication use, overall and for medications with known teratogenic risks, are largely unknown. This population-based cohort study in Ontario, Canada, 2004-2021, comprised all recognized pregnancies among individuals eligible for public drug plan coverage.

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Introduction: Large bone defects such as those encountered after failed total ankle replacement have previously been a relative contraindication to revision ankle replacement due to inadequate bone stock. We describe our experience and patient reported outcomes with a modular ankle replacement system with tibial and talar augments.

Methods: This is a retrospective case series analysis of patients who underwent a total ankle replacement using the INVISION system across 2 centers between 2016 and 2022.

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