Publications by authors named "I T Hogan"

Tridax procumbens (cotton buttons) is a flowering plant with a medicinal reputation for treating infections, wounds, diabetes, and liver and kidney diseases. The present research was conducted to evaluate the possible protective effects of the T. procumbens methanolic extract (TPME) on an experimentally induced type 2 diabetes rat model.

View Article and Find Full Text PDF

Background: Animal health surveillance is important in ensuring optimal animal health and welfare. Monitoring of diagnostic submissions, including post-mortem examination of carcasses, at the Department of Agriculture Food and the Marine laboratories, provides the basis for this type of passive surveillance in Ireland. The process requires engagement from veterinarians and farmers from all sectors of the agricultural spectrum.

View Article and Find Full Text PDF

In Ireland, the majority of coaches at non-elite level are volunteers and within the female-only team sport of women's Gaelic football, most qualified coaches are women. Yet, little is known on the club specific experiences of volunteer women coaches in non-elite sport. To address this gap, 11 women coaches, from three Gaelic Football clubs, were interviewed to explore the influence of the community-based club environment on their support and development in the role.

View Article and Find Full Text PDF

Background: The current study was the largest physical activity (PA) surveillance assessment of youth undertaken in Ireland in recent years. The purpose of this research was to assess the impact of social support, while controlling for age and screen time, on PA and sport participation, across a representative sample of Irish female youth.

Methods: A total of 3503 children (mean age: 13.

View Article and Find Full Text PDF
Article Synopsis
  • Endothelial to mesenchymal transition (EndMT) is linked to fibrosis and disease, but its exact mechanisms remain unclear, with focus on vessel-resident endovascular progenitors (EVP).
  • The transcription factors SOX9 and RBPJ play significant roles in regulating the numbers and fate of EVPs, where knocking out Sox9 reduces EVP numbers and minimizes pathological EndMT in wound healing.
  • Manipulating Sox9 and Rbpj levels affects gene expression related to EndMT, suggesting that targeting these pathways could lead to new therapies for fibrotic conditions.
View Article and Find Full Text PDF