Publications by authors named "I Stephenson"
Introduction: Understanding how RNA viral load changes (viral load kinetics) during acute infection in SARS-CoV-2 can help to identify when and which patients are most infectious. We seek to summarise existing data on the longitudinal RNA viral load kinetics of SARS-CoV-2 sampled from different parts of the respiratory tract (nose, nasopharynx, oropharynx, saliva and exhaled breath) and how this may vary with age, sex, ethnicity, immune status, disease severity, vaccination, treatment and virus variant.
Methods And Analysis: We will conduct a systematic review and meta-analysis, using studies identified through MEDLINE and EMBASE (via Ovid).
Article Synopsis
- A study was conducted to evaluate the effects of receiving the inactivated influenza vaccine (IIV) and SARS-CoV-2 vaccine at the same time compared to getting them separately among healthcare workers.
- Results showed that those who received both vaccines together had a lower rise in SARS-CoV-2 antibodies 1 month after vaccination, although this difference was not significant after 6 months.
- Overall, the concomitant vaccination did not seem to significantly affect the long-term immune response, suggesting that more research is needed to clarify these findings.
Article Synopsis
- People with HIV (PWH) have a higher risk of cardiovascular disease (CVD) compared to those without HIV, and the study aimed to evaluate their adherence to CVD medications and factors influencing non-adherence.
- Conducted at the University Hospitals of Leicester NHS Trust, this study analyzed data from 162 PWH, with findings indicating that about one-third of patients did not have prescribed medications detected in their urine, particularly highlighting issues with lipid-lowering agents.
- The analysis showed that a higher number of prescribed medications correlated with non-adherence, emphasizing the need for improved strategies to enhance medication compliance among PWH for better health outcomes.