Publications by authors named "I Stefanou"

A series of discrete elements simulations is presented for the study of fault gouges' frictional response. The gouge is considered to have previously undergone ultra-cataclastic flow and long-time consolidation loading. We explore the effect of different particle characteristics such as size, polydispersity, and also shearing velocities on gouge's response under the conditions met in the seismogenic zone.

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We propose a theory for preventing instabilities and inducing controlled, slow-slip in frictionally unstable systems, such as the Generalized-Burridge-Knopoff (GBK) model and seismic fault models. We exploit the dependence of friction on pressure and use it as a backdoor for altering the dynamics of the underlying dynamical system. We use the mathematical Theory of Control and, for the first time, we manage to (a) stabilize and restrict chaos in this kind of systems, (b) guarantee slow frictional dissipation and (c) tune the system toward desirable global asymptotic equilibria of lower energy.

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Article Synopsis
  • GISTs are a type of tumor in the gastrointestinal system, with varying characteristics and unclear molecular causes; microRNAs (miRNAs) play a role in cancer development by regulating gene expression.* -
  • The study aimed to identify specific miRNA expressions linked to gastric GISTs and to create miRNA profiles that could distinguish GIST patients from healthy individuals.* -
  • Results showed that several miRNAs were differently expressed in GIST patients, with hsa-miR-218-5p being the strongest predictor for GIST development, suggesting that machine learning can help assess GIST risk.*
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Black widow spider is endemic in the Mediterranean area and although envenomations are rare, may occasionally lead to death. We present a case of a 64-year-old female developing a rare variant of takotsubo, stress-induced, cardiomyopathy after a spider bite. This resulted in acute heart failure within 24  hours of the bite.

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Carbapenemase-producing Klebsiella pneumoniae strains (CP-Kps) are currently among the most important nosocomial pathogens. An observational study was conducted during 2009 to 2010 in two hospitals located in a high-prevalence area (Athens, Greece). The aims were (i) to evaluate the clinical outcome of patients with CP-Kp bloodstream infections (BSIs), (ii) to identify predictors of mortality, and (iii) to evaluate the various antibiotic schemes employed.

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