Publications by authors named "I Steenbruggen"

Background: Elevated exhaled nitric oxide fraction at a flow rate of 50 mL·s ( ) is an important indicator of T-helper 2-driven airway inflammation and may aid clinicians in the diagnosis and monitoring of asthma. This study aimed to derive Global Lung Function Initiative reference equations and the upper limit of normal for .

Methods: Available individual data were collated and harmonised using consensus-derived variables and definitions.

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Article Synopsis
  • The document updates the 2005 technical standards from the European Respiratory Society and American Thoracic Society for measuring lung volumes, incorporating new research and technological advancements.
  • Key revisions include improved standardization for linked spirometry, updated quality control protocols, and an expanded acceptability grading system for lung volume measurements.
  • The update also discusses emerging techniques like imaging, outlines future research directions, and addresses key questions in the field of pulmonary measurement.
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The use of self-reported race and ethnicity to interpret lung function measurements has historically assumed that the observed differences in lung function between racial and ethnic groups were because of thoracic cavity size differences relative to standing height. Very few studies have considered the influence of environmental and social determinants on pulmonary function. Consequently, the use of race and ethnicity-specific reference equations may further marginalize disadvantaged populations.

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