Transition metal-catalyzed synthesis of new 3-substituted coumarin derivatives as antibacterial and cytostatic agents.

The aim of this study was to synthesize new coumarin-based compounds and evaluate their antibacterial and antitumor potential. Using transition metal-catalyzed reactions, a series of 7-hydroxycoumarin derivatives were synthesized with aliphatic and aryl moiety attached directly at C-3 of the coumarin ring and through the ethynyl or 1,2,3-triazole linker. The 3-substituted coumarin derivative bearing bistrifluoromethylphenyl at the C-4 position of 1,2,3-triazole () showed strong and selective antiproliferative activity against cervical carcinoma cells.

Uncommon Non- Yeasts in Healthy Turkeys-Antimicrobial Susceptibility and Biochemical Characteristic of Trichosporon Isolates.

The microbiota of the gastrointestinal tract of humans and animals is inhabited by a diverse community of bacteria, fungi, protozoa, and viruses. In cases where there is an imbalance in the normal microflora or an immunosuppression on the part of the host, these opportunistic microorganisms can cause severe infections. The study presented here evaluates the biochemical and antifungal susceptibility features of spp.

A PROSPECTIVE STUDY TO ANALYZE THE SPECIFICITY OF CHLAMYDIAL HEAT SHOCK PROTEIN (CHSP60) ANTIBODIES TO DIAGNOSE TUBAL INFERTILITY.

Objective: The aim: To investigate the utility of testing for chlamydial heat shock protein 60 (CHSP60) antibodies in the diagnosis of tubal infertility.

Patients And Methods: Materials and methods: All the collected samples were assayed for IgM and IgG antibodies to chlamydia trachomatis and chlamydial heat shock protein 60 (CHSP60) by using immunofluorescence and enzyme-linked immunosorbent assay (ELISA) techniques, respectively.

Results: Results: There were no substantial differences between antibodies to C.

E-test Determination of Antifungal Susceptibility of Species Isolated from Turkeys.

Introduction: Candida species are a natural component of the intestinal tract microflora, but in favourable conditions they can cause superficial, mucosal, or even systemic candidiasis. Poultry production might be a source of human drug-resistant yeast infections, including spp. The limited data concerning the antifungal susceptibility of poultry isolates prompted us to carry out research to determine the susceptibility of isolates from turkey intestinal tracts.

Onshore mud volcanoes as a geological source of mercury: Case study from the Kerch Peninsula, Caucasus continental collision zone.

Three mud volcanoes (MVs) in the Kerch Peninsula were studied as a geological source of mercury. The study focused on total mercury (THg) concentrations in MV waters, mud masses and plants colonizing MV areas; gaseous elemental mercury (GEM) in the atmosphere above MVs; and sulfide mercury (HgS) and HgCl species in representative samples of mud masses. THg concentrations in the illite-smectite mud masses ranged from 38 to 920 ng/g.