Publications by authors named "I Sinescu"
Article Synopsis
- * There are significant differences in diagnosis and treatment approaches between developed and developing countries, and the prognosis largely relies on the spread of cancer to regional lymph nodes.
- * Recent improvements in imaging techniques, particularly PET CT, have enhanced the ability to detect lymph node metastasis early, leading to better survival rates for PeCa patients.
Introduction: Human immunodeficiency virus (HIV) is no longer considered a contraindication for kidney transplantation (KT). KT management in HIV patients is a complex process with challenges, such as drug interactions between immunosuppression and antiretroviral (ARV) therapy. In our country, no KT has been performed thus far in this category of patients.
View Article and Find Full Text PDFPurpose: Open ureteral reimplantation is considered the standard surgical approach to treat distal ureteral strictures or injuries. These procedures are increasingly performed in a minimally invasive and robotic-assisted manner. Notably, no series comparing perioperative outcomes and safety of the open vs.
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- - The study investigates the effectiveness of intraoperative cell salvage (IOCS) during kidney removal surgeries for patients with renal cell carcinoma (RCC) that involves tumor thrombus, aiming to reduce the need for blood transfusions.
- - Results from a multicenter analysis of 27 patients between 2012 and 2022 show that those who used IOCS had a significantly lower need for allogeneic blood transfusions and faced fewer complications.
- - The conclusion highlights that using salvaged blood during nephrectomy and thrombectomy procedures is safe and doesn't increase the risk of cancer recurrence or metastases.
Nowadays, the management of prostate cancer has become more and more challenging due to the increasing number of available treatment options, therapeutic agents, and our understanding of its carcinogenesis and disease progression. Moreover, currently available risk stratification systems used to facilitate clinical decision-making have limitations, particularly in providing a personalized and patient-centered management strategy. Although prognosis and prostate cancer-specific survival have improved in recent years, the heterogenous behavior of the disease among patients included in the same risk prognostic group negatively impacts not only our clinical decision-making but also oncological outcomes, irrespective of the treatment strategy.
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