Publications by authors named "I Sicard-Cras"
Article Synopsis
- The study aimed to assess the occurrence of the abscopal response (AR) in metastatic melanoma patients undergoing palliative radiotherapy, focusing on those receiving specific conditions of systemic treatments.
- Out of 118 patients analyzed, 15 (12.7%) exhibited an AR, showing significantly improved overall survival and progression-free survival compared to those without an AR.
- The findings suggest that AR is a rare but important indicator of better prognosis and may be enhanced by concurrent treatments like immunotherapy and infections during radiotherapy.
Habituation has been a topic of interest since the early 20th century. We summarise the characteristics of habituation, the proposed habituation mechanisms, the associated cortical responses and the link between habituation and cognitive development. Behavioural and neuroimaging studies have highlighted the early sensory abilities of foetuses and newborn infants, with preterm newborn infants exhibiting decreased habituation and dishabituation capabilities that increase their environmental vulnerability.
View Article and Find Full Text PDFBackground: Accurate assessments of pain in hospitalized preterm infants present a major challenge in improving the short- and long-term consequences associated with painful experiences. We evaluated the ability of the newborn infant parasympathetic evaluation (NIPE) index to detect acute procedural pain in preterm infants.
Methods: Different painful and stressful interventions were prospectively observed in preterm infants born at 25 + 0 to 35 + 6 weeks gestation.