and invasive central nervous system infection.

is a Gram-positive beta-hemolytic bacteria, also known as group A streptococci, that causes a range of infections. The most common presentation is acute pharyngitis; however, it is also implicated in skin and soft tissue infections, and less commonly bacteremia, osteomyelitis, pneumonia, otitis media and sinusitis. Group A streptococci infections of the central nervous system are exceedingly rare in the antibiotic era.

Integrated copy number and gene expression analysis detects a CREB1 association with Alzheimer's disease.

Genetic variation, both single-nucleotide variations and copy number variations (CNV), contribute to changes in gene expression. In some cases these variations are meaningfully correlated with disease states. We hypothesized that in a genetically heterogeneous disorder such as sporadic Alzheimer's disease (AD), utilizing gene expression as a quantitative trait and CNVs as a genetic marker map within the same individuals in the context of case-control status may increase the power to detect relevant loci.

Hypothalamic progesterone receptor-A mediates gonadotropin surges, self priming and receptivity in estrogen-primed female mice.

Ovarian progesterone (Prog) is an essential steroid hormone for the secretion of GnRH and reproductive behavior. It exerts primary effects through the progesterone receptor (PR). When analyzed separately in vitro, PR isoforms (PR-A, PR-B) display striking differences in transcriptional activity.

[Tissue irradiation doses in roentgenologic examinations of thoracic organs].

The paper is concerned with the results of experimental studies on the equivalent doses of irradiation of 11 organs and tissues by which one can calculate effective equivalent doses per study. Calculation were done on an anthropomorphous phantom of "conventional" man with the help of a thermoluminescent dosimetric system based on lithium fluoride. Equivalent doses were evaluated by the mean calculated value.

[Effect of the schedule of x-ray examinations on the radiation dosage of specific organs in patients].

It has been established on the basis of experimental dosimetric studies that during x-ray studies tissue doses of the irradiation of vital organs depend very little on the voltage of the x-ray tube in the range of 80-120 kV. It necessitates the use of x-ray radiation detectors with a high sensitivity as well as sparing technology of examination to decrease radiation exposure of patients. On condition of the constancy of tissue doses the main criterion for a chosen schedule is the informative value of an x-ray image.