Publications by authors named "I Sh Yakubova"

Article Synopsis
  • - The study aimed to analyze the chemical makeup of tooth enamel in two-day-old mice born to mothers on a high-cholesterol diet using energy dispersive X-ray spectroscopy.
  • - Mice were divided into two groups: one on a standard diet and the other on a cholesterol-rich diet, with enamel samples taken from their incisors to assess composition differences.
  • - Findings indicated that pups from hypercholesterolemic mothers had lower calcium levels and altered mineralization in their enamel, potentially leading to structural imperfections that could contribute to early childhood caries.
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Objective: The aim: To evaluate the mRNA expression of the key regulators of osteogenesis - osteocalcin and BMP-2 in the mouse embryos mandible (17th day of pregnancy) which were borne by females on high-cholesterol diet for 30 days before fertilization and throughout pregnancy.

Patients And Methods: Materials and methods: Experimental hypercholesterolemia (2%) was simulated by adding Cholesterol to the diet for 60 days. In experiment were used 40 mature female white mice that were randomly divided to control and experimental groups.

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Objective: The aim: To evaluate and compare the prevalence of gingivitis according to the PMA index in children aged 5 to 6 years in preschool with ASD and without disorders (Kyiv, Ukraine).

Patients And Methods: Materials and methods: Oral assessment was conduct on 69 children with ASD and 23 children without ASD aged 5 to 6 years. To determine the periodontal status it was used the papillary-marginal-alveolar index - PMA (according to Schour, Massler, in the modification of Parma).

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Objective: The aim: To reveal the effect of pyrophosphates on the tooth germ structure in the mandible of embryos (17th day of pregnancy) gestated by females, kept on a pyrophosphate-rich diet since 30 days before fertilization to gestation.

Patients And Methods: Materials and methods: The effect of food supplements was studied in «Overload phosphates model». Experiments were carried out on white nonlinear outbred mice with mass 25-28g (n= 40).

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Objective: The aim: Of our study was to measure the mRNA expression of the investigated odontogenesis factors in mandible tissue of mouse embryos (17th day of pregnancy) gestated by females, kept on a E450 rich diet since 30 days before fertilization to gestation.

Patients And Methods: Materials and methods: The effect of food supplements was studied in «Overload phosphates model». Experiments were carried out on white nonlinear outbred mice with mass 25-28g (n=40).

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