Radiation-associated angiosarcoma of the breast: An international multicenter analysis.

Introduction: Radiation-associated angiosarcoma (RAAS) is a rare and serious complication of breast irradiation. Due to the rarity of the condition, clinical experience is limited and publications on this topic include only retrospective studies or case reports.

Materials And Methods: All patients diagnosed with RAAS between January 2000 and December 2017 in twelve centers across the Czech Republic and Slovakia were evaluated.

[Breast conservative surgery after neoadjuvant oncologic treatment for breast carcinoma at the 1st Department of Surgery, 1st Faculty of Medicine of Charles University and General Teaching Hospital in Prague over a ten-year period (20042013)].

Introduction: Since the first breast conservative surgery following neoadjuvant oncotherapy performed in the 1990s, there has been a shift in indications, diagnostic, surgical and oncotherapeutic procedures. The aim of the study is to present the results of the comprehensive treatment of patients with breast conservative surgery performed after neoadjuvant oncologic treatment for breast cancer at our department of surgery.

Method: A retrospective study involving 96 patients operated on at our department between 2004 and 2013.

[Outcomes of complex therapy in female patients after breast-saving surgery for breast carcinoma at the 1st Surgical Department 1st Faculty of Medicine, Charles University and General University Hospital in Prague during a ten-year follow up period].

Introduction: Good longterm outcomes of complex therapy in operable breast cancer can be achieved mainly due to early diagnosis of the tumor, adequate radicality of surgery and adequate oncotherapy. The following outcome criteria are considered significant: long-term survival rate in complete remission, a number of locoregional recurrences and a number of reoperations or mastectomies required by results of final histological examination, patient satisfaction with a cosmetic result of their breast- saving surgery. Comparison of complex treatment results collected from patients who underwent breast-saving procedures performed for breast cancer at our department of surgery with data reported in literature.