Publications by authors named "I Saraiva"
There is increasing interest in the use of home-based monitoring in people with chronic lung diseases to improve access to care, support patient self-management, and facilitate the collection of information for clinical care and research. However, integration of home-based monitoring into clinical and research settings requires careful consideration of test performance and other attributes. There is no published guidance from professional respiratory societies to advance the science of home-based monitoring for chronic lung disease.
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- Persistent acute kidney injury (pAKI) has a worse prognosis than transient acute kidney injury (AKI) in critically ill patients, but its impact and definitions are less understood in organ transplant recipients.
- A systematic review of 25 studies involving 6,330 patients showed a wide variation in the incidence and definitions of pAKI among heart, lung, and liver transplant recipients.
- pAKI is linked to higher rates of new chronic kidney disease, graft dysfunction, and long-term mortality, highlighting the need for standardized definitions in future research.
Article Synopsis
- - Lung cancer is a major global health issue, and low-dose computed tomography (LDCT) screening can reduce mortality rates by up to 25%, making it a cost-effective solution that European countries are encouraged to explore for implementation.
- - A task force reviewed literature and engaged in discussions to develop recommendations for launching lung cancer screening programs in Portugal, focusing on the guidelines of the World Health Organization tailored to the local healthcare system.
- - Key areas covered in the recommendations include identifying eligible populations, invitation methods, radiological requirements, result reporting, referral processes, and the integration of smoking cessation programs as essential for effective lung cancer screening.
Introduction: Acute kidney injury (AKI) is a common complication of sepsis associated with increased risk of death. Preclinical data and observational human studies suggest that activation of AMP-activated protein kinase, an ubiquitous master regulator of energy that can limit mitochondrial injury, with metformin may protect against sepsis-associated AKI (SA-AKI) and mortality. The Randomized Clinical Trial of the Safety and FeasibiLity of Metformin as a Treatment for sepsis-associated AKI (LiMiT AKI) aims to evaluate the safety and feasibility of enteral metformin in patients with sepsis at risk of developing SA-AKI.
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