Publications by authors named "I Samina"
Article Synopsis
- Birds, particularly nestlings, are hard to identify by gender early on, making it challenging to manage unwanted chicks in hatcheries without welfare concerns regarding culling.
- A new method using Thymine-DNA Glycosylase (TDG) allows for sex determination in chickens without requiring PCR, effectively recognizing and correcting thymine/guanine mismatches in their DNA.
- Initial laboratory findings suggest that this technique can directly detect chicken gender through specific DNA sequences, and with further development, it may be usable outside of lab environments where PCR is impractical.
The protective efficacy and immunogenicity of a chimeric peptide against West Nile virus (WNV) was evaluated. This virus is the aetiological agent of West Nile fever, which has recently emerged in the western hemisphere. The rapid spread of WNV throughout North America, as well as the constantly changing epidemiology and transmission of the virus by blood transfusion and transplantation, have raised major public-health concerns.
View Article and Find Full Text PDFWest Nile virus (WNV) is a mosquito-borne disease found most commonly in Africa, west Asia, and the Middle East, where up to 40% of the human population possesses antibodies. It is an emerging disease in the United States, since 1999 and has spread all over the US and Canada. The virus is maintained in nature in a mosquito-bird-mosquito cycle (primarily Culex), with human horses and other animals serving as incidental hosts.
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- West Nile Virus (WNV) is common in Israel, and many people have developed antibodies against it through exposure, leading researchers to explore its use in treating severe infections.
- OMRIX Biopharmaceuticals developed a method to select plasma from Israeli blood donors with anti-WNV antibodies to create a more potent treatment known as WNIG, which is significantly stronger than regular IVIG.
- In experiments on mice, WNIG demonstrated much higher effectiveness in preventing and treating WNV infections, especially in immunosuppressed mice, suggesting it could be a valuable therapy for patients with severe WNV.
Studies were performed with an inactivated vaccine against the mosquito-borne flavivirus, West Nile virus (WNV). The mammalian cell line, PER.C6, was selected as the platform for WNV growth since both the neurovirulent strains NY99 and ISR98 that cause epidemics in humans and high mortality in geese, respectively, could be propagated to high titers (10(9) to 10(10)TCID(50)/ml) on these cells.
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