Raw Ocimum sanctum L. leaf extract modulates the pharmacokinetic of ceftriaxone and increases its bioavailability in staphylococcal mastitis.

Background: To study the pharmacokinetic interaction of cephalosporin antibiotic ceftriaxone (CFT) with raw undiluted Ocimum sanctum L. leaf juice in chronic staphylococcal mastitis in caprine.

Materials And Methods: Chronic inflammation of the udder was evoked in goats by Staphylococcus aureus (J638) intracisternal inoculation 2000 cfu for 30 days into the left udder.

A hybrid approach for power quality event identification in power systems: Elasticnet Regression decomposition and optimized probabilistic neural networks.

The transformation of traditional grid networks towards smart-grid and microgrid concepts raises many critical issues, and quality in the power supply is one of the prominent ones that needs further research. Developing and applying power quality (PQ) recognition methods with efficient and reliable analysis are essential to the fast-growing issues related to modern smart power distribution systems. In this regard, a hybrid algorithm is proposed for PQ events detection and classification using Elasticnet Regression-based Variational Mode Decomposition (ER-VMD) and Salp Swarm Algorithm optimized Probabilistic Neural Network (SSA-PNN).

In-silico insights of ESBL variants and tracking the probable sources of ESBL-producing Escherichia coli in a small-scale poultry farm.

Commercial broiler farms face challenges of extended spectrum beta-lactamase (ESBL)-producing Escherichia coli transmitted from both vertical and horizontal routes. Understanding the dynamics of ESBL-E. coli transmission in compromised biosecurity settings of small-scale rural poultry farms is essential.

Stray Dogs (Mongrels) Are Potent Reservoir of Drug-Resistant Pathogens: A Study in Peri-Urban Areas of Kolkata, India.

This study depicts the drug-resistance and phylogenomic characteristics of 365 (EC) and 76 (KP) isolated from stray dogs (293) in and around Kolkata, India. Initial screening found 59 isolates, including 48 and 11 KP multidrug resistant, which included 33 extended-spectrum β-lactamase, 41 AmpC β-lactamase and 18 metallo-β-lactamase producers carrying (11) and (7) genes. Majority of them had the resistant genes such as (33), (18), (4), (17), (2), (2), (15), (13), (2) and (2), S (15), B (3), (14), A (26), B (14), -1 (25), A (2) and B (6), in addition to adherence genes such as A (33), A (27), C (13), A (33), A (38), and S (39).