Clay Tailings Flocculated in Seawater and Industrial Water: Analysis of Aggregates, Sedimentation, and Supernatant Quality.

High-molecular-weight anionic polyacrylamide was used to analyze the effect of kaolin on the structure of particle aggregates formed in freshwater and seawater. Batch flocculation experiments were performed to determine the size of the flocculated aggregates over time by using focused beam reflectance measurements. Sedimentation tests were performed to analyze the settling rate of the solid-liquid interface and the turbidity of the supernatant.

Atypical pattern of response in rectal cancer after neoadjuvant pembrolizumab treatment: a case report, literature review, and proposed management model.

Background: Immunotherapy is the first-line treatment in patients with advanced microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) colorectal cancer (CRC). Although immune checkpoint inhibitors (ICIs) for locally advanced rectal cancer (LARC) are not yet a standard, the results are very encouraging and raise the question of whether patients with clinical complete response (cCR) could receive nonoperative management (NOM). However, different patterns of response have challenged management strategies.

Bioleaching Modeling-A Review.

The leaching of minerals is one of the main unit operations in the metal dissolution process, and in turn it is a process that generates fewer environmental liabilities compared to pyrometallurgical processes. As an alternative to conventional leaching methods, the use of microorganisms in mineral treatment processes has become widespread in recent decades, due to advantages such as the non-production of emissions or pollution, energy savings, low process costs, products compatible with the environment, and increases in the benefit of low-grade mining deposits. The purpose of this work is to introduce the theoretical foundations associated with modeling the process of bioleaching, mainly the modeling of mineral recovery rates.

Molecular mechanisms of ischemia and glutamate excitotoxicity.

Excitotoxicity is classically defined as the neuronal damage caused by the excessive release of glutamate, and subsequent activation of excitatory plasma membrane receptors. In the mammalian brain, this phenomenon is mainly driven by excessive activation of glutamate receptors (GRs). Excitotoxicity is common to several chronic disorders of the Central Nervous System (CNS) and is considered the primary mechanism of neuronal loss of function and cell death in acute CNS diseases (e.