Publications by authors named "I Sakaida"
Introduction: Patients with hepatitis virus-related hepatocellular carcinoma (viral HCC) are decreasing as hepatitis control improves, but those with non-viral-related HCC (non-viral HCC) are increasing in Japan. No established surveillance system exists for patients with non-viral HCC, so they are often diagnosed at an advanced stage. To address this, we performed this study.
View Article and Find Full Text PDFIntroduction: As the incidence of gastric cancer (GC) is increasing in East Asia including Japan, a simple blood test for early GC is needed as an alternative to upper gastrointestinal (UGI) endoscopy. We performed this study to address this issue.
Methods: We collected serum samples from 319 participants comprising 225 healthy subjects without GC (control group) and 94 patients with early GC (early GC group).
Article Synopsis
- The fecal immunochemical test (FIT) is commonly used for colorectal cancer screening but lacks sensitivity for advanced colorectal adenoma detection.
- A study combined FIT with fecal DNA testing of methylated somatostatin (SST) to enhance diagnostic accuracy for advanced colorectal adenoma.
- The new FAMS (FIT, age, methylated SST) index demonstrated significantly improved sensitivity (56.4%) compared to FIT alone (29.1%), suggesting it could be a more effective screening tool.