Olanzapine-Induced Acute Pulmonary Embolism.

Pulmonary embolism is defined as the abrupt obliteration of the trunk or a branch of the pulmonary artery by an embolus most often from a deep vein thrombosis of the lower limbs. It is serious, underdiagnosed, and can be life-threatening. We report the case of a patient who presented with a massive acute pulmonary embolism while taking olanzapine.

Leveraging chorionic villus biopsies for the derivation of patient-specific trophoblast stem cells.

Human trophoblast stem () cells are an informative in vitro model for the generation and testing of biologically meaningful hypotheses. The goal of this project was to derive patient-specific TS cell lines from clinically available chorionic villus sampling biopsies. Cell outgrowths were captured from human chorionic villus tissue specimens cultured in modified human TS cell medium.

The Epidemiological, Clinical, and Therapeutic Profile of Bipolar Patients in Eastern Morocco.

Introduction:  Bipolar disorder is a severe psychiatric disorder. The objective of our study is to describe the epidemiological, clinical, and therapeutic profile of patients followed for bipolar disorder in this hospital.

Materials And Methods: This is a cross-sectional, descriptive study conducted over a period of two years within the mental health and psychiatric diseases department of the Mohammed VI University Hospital in Oujda, Morocco, including 206 patients followed for bipolar disorder on an outpatient basis or hospitalized in one of the departments of the hospital.

Actin cytoskeletal regulation of ciliogenesis in development and disease.

Primary cilia are antenna-like sensory organelles that are evolutionarily conserved in nearly all modern eukaryotes, from the single-celled green alga, Chlamydomonas reinhardtii, to vertebrates and mammals. Cilia are microtubule-based cellular projections that have adapted to perform a broad range of species-specific functions, from cell motility to detection of light and the transduction of extracellular mechanical and chemical signals. These functions render cilia essential for organismal development and survival.

Distribution of residence time in rotary-drum composting and implications for hygienization.

Rotary drums enable rapid composting compared to static systems. Residence times (RT) of 3-5 days are commonly applied to fulfill sanitary requirements and ensure the initial stabilization of organic matter. Practically, RT distribution (RTD) implies that a portion of the feed is discharged earlier than the mean RT, which may not guarantee safe application of the end product.