Publications by authors named "I S Voĭt"

Article Synopsis
  • Patients with multiple myeloma (MM) receive mRNA vaccines to decrease COVID-19 mortality, but their immune responses to vaccination can vary significantly.
  • A study analyzed immune cells from 58 MM patients during and after vaccination and breakthrough infections, revealing that successful vaccine responders had distinct immune cell profiles with strong cytokine responses.
  • The findings suggest that both vaccinated patients and those who experienced breakthrough infections showed similar immune patterns, highlighting potential avenues for improving vaccination strategies for immunocompromised individuals.
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Under the effect of intense stressful stimuli baboons developed a depressive state. The disintegration of individual and social behaviour correlates with changes in functional activity of steroid-producing glands and the dynamics of the blood endorphin concentration, thus suggesting involvement of the opioid peptide system and the hypophyseal-gonadal complex in mechanisms of stress-induced depressive states.

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As a result of intensive stressful stimuli hamadryas baboons developed, depending on their hierarchic status, depression-like states varying in severity. Their development correlated with a drastic release of biogenic amines, activation of pituitary-adrenal system and inhibition of hormonal function of the gonads. It is shown that dominant and low-rank monkeys, in spite of the differences in their initial psychoemotional states and in the blood levels of mediators and hormones, demonstrated marked disintegration in their individual and social behavior.

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