Publications by authors named "I S Vaithilingam"
Background: Peritonitis is the common complication among Continuous Ambulatory Peritoneal Dialysis (CAPD) patients. This study is aimed to identify the factors predicting clinical outcomes of peritonitis in patients undergoing CAPD and the demographic, clinical and microbiological features of CAPD patients who were diagnosed with peritonitis.
Materials And Methods: This is a retrospective observational study conducted to identify factors predicting clinical outcomes of CAPD associated peritonitis over a four-year period in Taiping Hospital, Malaysia.
Article Synopsis
- TRK-100STP is a sustained-release version of beraprost sodium aimed at improving kidney function in patients with chronic kidney disease and was tested against placebos.
- The study, named CASSIOPEIR, involved nearly 900 patients over a period of up to 4 years and evaluated the effectiveness of two doses of the drug (120 μg and 240 μg) compared to a placebo.
- Results showed no significant advantages of TRK-100STP over placebo regarding kidney-related outcomes, and the rates of adverse events were similar across all groups.
Randomized controlled trial to compare the efficacy and safety of oral paricalcitol with oral calcitriol in dialysis patients with secondary hyperparathyroidism.
Nephrology (Carlton)
March 2013
Aim: The objective of the study was to compare the efficacy and safety of oral paricalcitol with oral calcitriol for treating secondary hyperparathyroidism.
Methods: We conducted the first multicenter open-labelled parallel group randomized controlled trial in 66 patients on dialysis. Patients were randomized to paricalcitol or calcitriol at a 3:1 dose ratio and adjusted to maintain intact parathyroid hormone (iPTH) level between 150-300 pg/mL, serum calcium ≤2.
Background: Control of serum phosphate remains a difficult clinical issue in most hemodialysis (HD) patients. This study examines 2 nonpharmacological approaches to improving phosphate control in HD patients.
Methods: First, 9 stable HD patients underwent dialysis in random fashion for either 4 hours 3 times weekly or 5 hours 3 times weekly.