Publications by authors named "I S Tarasova"
[Clinical efficacy of carbohydrate preloading in reconstructive esophageal surgery].
Khirurgiia (Mosk)
December 2024
Objective: To evaluate clinical efficacy of preoperative carbohydrate loading as a component of ERAS in esophageal reconstructive surgery.
Material And Methods: Post hoc analysis included 162 patients who underwent esophageal reconstructive interventions with ERAS principles between 2014 and 2024. The main group (=61, CHO+) included patients who were metabolically loaded with carbohydrates in preoperative period with 12.
Article Synopsis
- * All patients underwent a surgical procedure called fundoplication, and results were assessed 6 and 12 months post-surgery.
- * After surgery, 92.8% experienced relief from reflux symptoms, and 94.5% showed improvement in hemoglobin and iron levels without needing iron supplements.
Gallbladder stones are present in 10-20 % of the population of Western countries, and the incidence rate has almost tripled over the past 30 years. Asymptomatic cholecystitis is more common than it is mentioned in the literature. Approximately 80 % of the GI have no clinical manifestations.
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- Multidrug-resistant strains, particularly those linked to farm animals, are a growing concern for human health due to their ability to cause severe intestinal and extraintestinal diseases.
- This study focuses on APEC 36, a strain isolated from a chicken with a serious infection, analyzing its genome and finding it has multiple antibiotic resistance mechanisms, mainly antibiotic efflux.
- APEC 36 also contains unique genetic traits, such as a rare beta-lactamase variant and genes linked to toxins and iron uptake, indicating that it could pose significant threats to human health.
Current stage of proteomic research in the field of biology, medicine, development of new drugs, population screening, or personalized approaches to therapy dictates the need to analyze large sets of samples within the reasonable experimental time. Until recently, mass spectrometry measurements in proteomics were characterized as unique in identifying and quantifying cellular protein composition, but low throughput, requiring many hours to analyze a single sample. This was in conflict with the dynamics of changes in biological systems at the whole cellular proteome level upon the influence of external and internal factors.
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