[Peculiarities of diabetes mellitus course in chronic pancreatitis].

In order to identify features of the course pancreatic diabetes and discussion of the principles of conservative therapy were examined 66 patients with CP in age of 30 to 65 years (55 men, 11 women). Among them in 22 cases disease was followed with formation of calcification of pancreas, 13 - pancreatic cysts, and 5 revealed pseudo tumor form of CP, 10 patients had clinical and laboratory evidence of diabetes. Concerning CP complicated course were performed 14 resection and 11 draining operations on the pancreas.

[The specific features of pancreatic incretory dysfunction in chronic pancreatitis].

Aim: To reveal the specific features of pancreatogenic diabetes mellitus (DM) and to discuss the principles of its medical therapy.

Subjects And Methods: Sixty-six patients (55 men and 11 women) aged 30 to 65 years with chronic pancreatitis (CP) were examined. The disease was accompanied with pancreatic calcification and cyst formation in 22 and 13 patients, respectively; 5 patients were found to have a pseudotumorous form of CP and 10 had clinically and laboratorily verified DM.

[Effect of pancreatic secretory trypsin gene mutations on the development of chronic pancreatitis].

For the first time the relationship between mutations in the pancreatic secretory trypsin inhibitor (SPINK1) in humans and the development of chronic pancreatitis was established in 2000. By mid 2011 the number of studies on the influence of SPINK1 gene mutations on the development of pancreatitis exceeds 250, the results vary greatly. According to modern concepts, mutations in SPINK1 gene are associated with the development of both acute and chronic pancreatitis, and are defined in all etiological forms.

[Cytomegalovirus infection in patients with ulcerative colitis].

Aim: Adjusting therapy of patients with ulcerative colitis (UC) regarding their cytomegalovirus (CMV)--status.

Materials And Methods: 40 patients were included, mean age--44.3 +/- 3.

[Effect of hepatitis C virus genotype on viral load and clinical-laboratory characteristics of liver disease].

Unlabelled: Aim of the work was to examine the influence of HCV genotype on the clinical features of chronic hepatitis and cirrhosis.

Materials And Methods: Were examined 9.715 patients under treatment in hospital gastroenterological for the presence of hepatitis C virus.