Automated homogeneous immunoassay for gentamicin on the dimension clinical chemistry system.

Background: Monitoring of the concentration of gentamicin in serum and plasma during therapy is widely recommended and practiced in hospitals. Our aim was to develop a homogeneous immunoassay based on particle-enhanced turbidimetric inhibition immunoassay technology to quantify gentamicin on the Dimension clinical chemistry system.

Methods: Assay performance was assessed on each of the Dimension models in a 15-instrument interlaboratory comparison study.

Development and analytical performance of an automated screening method for cannabinoids on the Dimension clinical chemistry system.

A fully automated, random access method for the determination of cannabinoids (UTHC) was developed for the Dimension AR and XL clinical chemistry systems. The method utilizes Abuscreen ONLINE reagents and a multianalyte liquid calibrator containing 11-nor-Delta(9)-THC-9-carboxylic acid. Within-run and total reproducibility, determined using NCCLS protocol EP5- T2, was less than 0.