Structural, photoluminescence, and optical characteristics of a Sm -doped lead borate-strontium-tungsten glass system: Evaluation of Judd-Ofelt intensity parameters and radiative properties.

In this study, the melt quenching approach is used to synthesize a lead borate-strontium-based glass system doped with samarium ions. Modifications in the glass network structure arising from the addition of various concentrations of Sm ions were investigated via Fourier transform infrared (FTIR) spectroscopy. FTIR analysis revealed B-O-B bridges, BO , and BO units are present.

Differential effects of phototherapy, adalimumab and betamethasone-calcipotriol on effector and regulatory T cells in psoriasis.

Background: Psoriasis is a chronic T-cell-mediated skin disease with marked social and economic burdens. Current treatments are unsatisfactory, with unpredictable remission times and incompletely understood modes of action. Recent advances in our understanding of the pathogenesis of psoriasis have identified the imbalance between CD4 T effector cells, particularly the T helper (Th)17 subset, and regulatory T cells (Tregs) as key to the development of psoriatic lesions, and therefore a novel therapeutic target.