Publications by authors named "I S Kaya"
Background: Contemporary stroke care is moving towards more holistic and patient-centred integrated approaches, however, there is need to develop high quality evidence for interventions that benefit patients as part of this approach.
Aim: This study aims to identify the types of integrated care management strategies that exist for people with stroke, to determine whether stroke management pathways impact patient outcomes, and to identify elements of integrated stroke care that were effective at improving outcomes.
Design: Systematic review with meta-analysis.
Multiomics analysis of single tissue sections using matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) provides comprehensive molecular insights. However, optimizing tissue sample preparation for MALDI-MSI to achieve high sensitivity and reproducibility for various biomolecules, such as lipids, -glycans, and tryptic peptides, presents a significant challenge. This study introduces a robust and reproducible protocol for the comprehensive sequential analysis of the latter molecules using MALDI-MSI in fresh-frozen rodent brain tissue samples.
View Article and Find Full Text PDFBackground: The effect of conservative treatments on sleep quality in carpal tunnel syndrome is unclear.
Purpose: Comparing the effect of splinting and kinesiotaping in carpal tunnel syndrome on functional status, pain, grip strength, nerve cross-sectional area and sleep quality.
Study Design: Randomized controlled study.
Objective: This study aimed to assess the efficacy of a novel modified asymmetric chondro-perichondrial island graft in tympanoplasty. The design features a longer anterior segment compared to the posterior segment, addressing limitations of symmetrical grafts. We investigated the impact of this modified graft on hearing improvement and graft success rates in patients undergoing tympanoplasty surgery.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates different strategies for venoarterial extracorporeal membrane oxygenation (V-A ECMO) in patients, examining the effectiveness of various cannulation sites and the use of intra-aortic balloon pump (IABP).
- Researchers categorized patients into two main groups: those receiving isolated V-A ECMO and those receiving V-A ECMO with IABP, and further divided them based on cannulation sites (e.g., central, axillo-femoral).
- Results showed no significant differences in organ perfusion across the different cannulation sites or with IABP support, suggesting that the choice of cannulation site should be tailored to individual patient needs rather than based on a one-size-fits-all approach