Publications by authors named "I S Gruzdev"

Objective: To develop diagnostic radiomic model-based algorithm for pancreatic ductal adenocarcinoma (PDAC) grade prediction.

Methods: Ninety-one patients with histologically confirmed PDAC and preoperative CT were divided into subgroups based on tumor grade. Two histology-blinded radiologists independently segmented lesions for quantitative texture analysis in all contrast enhancement phases.

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Radiomics (or texture analysis) is a new imaging analysis technique that allows calculating the distribution of texture features of pixel and voxel values depend on the type of ROI (3D or 2D), their relationships in the image. Depending on the software, up to several thousand texture elements can be obtained. Radiomics opens up wide opportunities for differential diagnosis and prognosis of pancreatic neoplasias.

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Purpose: To evaluate the reproducibility of textural features of pancreatic neuroendocrine neoplasms (PNENs), obtained under various CT-scanning conditions.

Methods And Materials: We included 12 patients with PNENs and 2 contrast enhanced CT (CECT): 1) from our center according to standard CT-protocol; 2) from another institution. Two radiologists independently segmented the entire neoplasm volume using a 3D region of interest by LIFEx application on the arterial phase and then copied it to the other phases.

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Introduction: Tumors of the diaphragm are uncommon. The overwhelming number of cases is metastatic combined with metastases to the liver, lungs and other organs. Only a minority of cases are described as solitary lesions.

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The balance studies among the high-qualified adult sportsmen during the winter period of practices had shown that of the day of a 30-km cross the contents of iron, copper and manganese in the food ration fell to the lowest level of the physiological standard of people not going into sports due to sufficient physical load the process of microcomponents' secretion through bowels and kidneys was outstripping their replenishment from food. The balance of all three microcomponents was negative. During the following three days after the cross due to disbalanced food ration caused by the content of microcomponents the losses of iron and copper were not compensated.

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