Publications by authors named "I S Grewal"

Objectives: The midline lateral parapatellar (LP) approach has been shown in a cadaveric study to provide superior articular exposure compared to the anterolateral approach (AL). The purpose of this study was to report on outcomes and complications with the LP approach.

Methods: Design: Retrospective comparative cohort study and prospective cohort.

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Cardiovascular diseases (CVDs) are the major cause of mortality worldwide, emphasizing the critical need for timely and accurate diagnosis. Artificial intelligence (AI) and machine learning (ML) have become revolutionary tools in the healthcare system with significant potential for cardiovascular diagnosis and imaging. AI and ML techniques, including supervised and unsupervised learning, logistic regression, deep learning models, neural networks, and convolutional neural networks (CNNs), have significantly advanced cardiovascular imaging.

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Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by renal phosphate wasting and impaired bone mineralization secondary to secretion of fibroblast growth factor 23 (FGF23) from mesenchymal tumors (phosphaturic mesenchymal tumors, PMTs). PMTs have wide anatomical distribution but typically affect extremities and craniofacial bones. Diagnosis of TIO/PMT is often delayed, and a high index of suspicion is essential in patients with unexplained fractures, but many physicians lack familiarity with TIO/PMT and simply attribute fractures to the more common diagnosis of osteoporosis.

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Background: Despite the proven effectiveness of endovascular therapy (EVT) in acute ischemic strokes (AIS) involving anterior circulation large vessel occlusions, isolated posterior cerebral artery (PCA) occlusions (iPCAo) remain underexplored in clinical trials. This study investigates the comparative effectiveness and safety of EVT against medical management (MM) in patients with iPCAo.

Methods: This multinational, multicenter propensity score-weighted study analyzed data from the Multicenter Analysis of primary Distal medium vessel occlusions: effect of Mechanical Thrombectomy (MAD-MT) registry, involving 37 centers across North America, Asia, and Europe.

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Article Synopsis
  • This study aimed to create a comprehensive consensus on managing myopia in children and young people across the UK and Ireland through a Delphi method involving 34 expert optometrists and ophthalmologists.
  • The panel agreed on 131 statements, emphasizing the need for parental discussions on interventions for myopia developed before age 13, publicly funded options for those at risk, and the consideration of individual hobbies and lifestyles in choosing treatment.
  • Future research is essential to better identify at-risk patients, assess the effectiveness of treatments, and adapt management strategies as new evidence arises.
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