Uncertainty Quantification and Flagging of Unreliable Predictions in Predicting Mass Spectrometry-Related Properties of Small Molecules Using Machine Learning.

Mass spectral identification (in particular, in metabolomics) can be refined by comparing the observed and predicted properties of molecules, such as chromatographic retention. Significant advancements have been made in predicting these values using machine learning and deep learning. Usually, model predictions do not contain any indication of the possible error (uncertainty) or only one criterion is used for this purpose.

[The method of calculation of maximally admissable mass of adipose-cutaneous flap, excised during abdominoplasty].

The dependence of a hypercoagulation state occurrence from value of the adipose-cutaneous flap mass, excised while performing abdominoplasty, was established, using the logistic regression method, in patients, suffering the anterior abdominal wall cosmetic defects and obesity. The possibility the hypercoagulation state occurrence raises nonlinearly together with such of the excised flap mass (% EFM), it exceeds 50% (high risk of hypercoagulation occurrence), when the EFM value constitutes 5.1% of the body mass.

[Antiatherogenic effect of abdominoplasty in patients with anterior abdominal wall deformity and obesity].

The impact on a lipids metabolism of a certain volume of fat tissue extraction from organism was investigated. With that objective there was determined the lipids content in a blood serum before and on a 14th day after abdominoplasty. In 73 patients (the main group) surgical interventions were performed on the organs of abdominal cavity, small pelvis and anterior abdominal wall with a simultant abdominoplasty, in 59 patients (a comparison group) abdominoplasty was not performed.

[Functional-anatomical prerequisites of revascularization of the femoro-popliteal arterial segment].

Improved results of surgical treatment of patients with critical ischemia of lower extremities can be obtained by using the collateral bed. The condition of the profound femoral artery and the popliteal artery, especially in the zone of its trifurcation, is of the greatest significance for the decision on the volume of surgery. The carrying capacity of the collateral bed of the profound femoral artery in occlusion of the femoral artery was on average 284 ml/min.