[Effectiveness of early invasive strategy of treatment of angina of new onset].

Aim of the study was to assess effectiveness of early invasive strategy of treatment of angina of new onset (ANO). We conducted comparative assessment on invasive and noninvasive risk estimation in 106 patients admitted to N.V.

[Different methods of myocardial revascularization in non-stable stenocardia].

The purpose of the study was to evaluate different methods of myocardial revascularization. Three hundred and twenty-two patients with non-stable stenocardia were divided into two groups: group one consisted of 226 patients with mono-, bi-, or tri-vascular lesion of the coronary arteries (CA), who underwent percutaneous coronary intervention (PCCI) on the symptom-related CA (128 patients) or coronary bypass surgery (CBS) without cardiopulmonary bypass (59 patients); group two consisted of 96 patients with tri-vascular lesion of CA only, who underwent CBS with cardiopulmonary bypass (CPB) (32 patients) or without CPB (52 patients). The rest patients in both groups received drug therapy.

[A novel method of analysis of ligand-polynucleotide adsorption isotherms].

The adsorption of ethidium bromide on the synthetic double-stranded polyribonucleotide poly(G)poly(C) was investigated by adsorption spectroscopy. The adsorption isotherms were analyzed in the framework of the Crothers-Gursky model. It was shown that adsorption parameters (e.

[Pumpan in the treatment of ischemic heart disease associated with arterial hypertension].

Aim: To study effectiveness of natural combined medicine pumpan in patients with ischemic heart disease (IHD) including cases with concomitant arterial hypertension (AH).

Material And Methods: 35 patients with different forms of IHD (myocardial infarction, stable and unstable angina pectoris of functional class III-IV) received conventional treatment combined with pumpan given for 7-11 weeks. Changes in clinical condition, biochemical blood indices, ECG, echo-CG, 24-h arterial pressure monitoring data were investigated.

[The study of the interaction of antineoplastic drugs mitoxantrone and ametantrone with DNA using the analysis of changes in circular dichroism spectra].

The influence of the ionic strength and temperature of medium on the changes in the geometry of the double stranded DNA of different nucleotide content upon the formation of complexes with antitumor drugs mitoxantrone and ametantrone was investigated. It is shown that from circular dichroism spectra it is possible to determine the relative intensity of changes in the geometry of DNA double helix upon binding with the drugs investigated. The binding of one ametantrone molecule causes greater changes in the geometry of DNA double helix than the binding of mitoxantrone.