Publications by authors named "I S An"
Article Synopsis
- Sleep disturbances are common in children with autism spectrum disorder (ASD) and are linked to the severity of their symptoms, especially memory issues.* -
- In a study using a mouse model of ASD, researchers found that non-rapid eye movement sleep (NREMs) was fragmented, which correlated with increased activity in certain brain neurons during sleep.* -
- By inhibiting these neurons, the study showed that sleep could be stabilized and memory improved, highlighting the significant role of the locus coeruleus noradrenergic system in regulating both sleep and memory in ASD.*
Pediatric Cutaneous Leishmaniasis in Turkey: A Retrospective Analysis of 8047 Cases.
Acta Dermatovenerol Croat
March 2024
Cutaneous leishmaniasis (CL) is common in the pediatric population, but there are only a limited number of studies focused on the clinical and epidemiological characteristics of patients in this age group. In this study, our objective was to investigate the epidemiological and clinical characteristics of pediatric subjects diagnosed with CL. A total of 8047 patients who had been diagnosed with CL between 2010 and 2021 in an endemic region were included in this retrospective study.
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- This study aimed to identify atypical clinical presentations of cutaneous leishmaniasis (CL) in Şanlıurfa province, encompassing a retrospective analysis of 213 patients with non-standard symptoms out of 1,751 diagnosed cases between 2019 and 2022.
- The prevalence of atypical CL was found to be 12.1%, with common atypical lesions including lupoid, erysipeloid, and impetiginous types, along with many others resembling various skin conditions and diseases.
- The research highlights that CL can mimic a wide range of infectious, inflammatory, and neoplastic disorders, stressing the importance of thorough differential diagnosis for persistent non-healing skin lesions, especially in areas where CL is
Cutaneous findings and treatment responses of lipoid proteinosis patients.
Int J Dermatol
January 2025
Article Synopsis
- Lipoid proteinosis (LP) is a rare genetic disorder that leads to the buildup of material in various tissues, causing skin and mucosal changes; this study aimed to assess various skin symptoms and treatment outcomes in LP patients.
- 41 patients were included in the study, with diagnoses confirmed either through gene mutation analysis or clinical examination; most patients showed skin thickening and a variety of other dermatological features.
- Treatments included acitretin, which showed no effect, and systemic steroids, which effectively resolved blisters, highlighting the need for further research on treatment efficacy in LP.
Article Synopsis
- The study investigates the frequency and types of cutaneous leishmaniasis (CL) lesions found in the nasal area, highlighting the potential for misdiagnosis with other inflammatory or tumoral diseases.
- Conducted retrospectively in Şanlıurfa, Turkey, between September 2022 and October 2023, it included 278 CL patients, with 34 (12.2%) showing nasal involvement, predominantly affecting males.
- The findings reveal that the majority of nasal lesions were acute, with various morphological types observed, and emphasize the importance for physicians in endemic regions to consider CL in diagnoses for nasal lesions to enable early treatment and prevent complications.